Science blog

Exploring science at the British Library

80 posts categorized "Research"

05 October 2015

New opportunities for collaborative PhD research exploring the British Library’s science collections

Applications for collaborative PhD research around the British Library’s science collections are now open to UK universities and other HEIs

AHRC logoThe British Library is looking for university partners to co-supervise collaborative PhD research projects that will open up unexplored aspects of its science collections.  Funding is available from the Arts & Humanities Research Council (AHRC) Collaborative Doctoral Partnerships programme, through which the Library works with UK universities or other eligible Higher Education Institutes around strategic research themes.

Our current CDP opportunities include a project to examine the culture and evolution of scientific research, drawing on scientists’ personal archives, and another project to develop digital tools for the investigation of scientific knowledge in the 17th and 18th centuries:

The Working Life of Scientists: Exploring the Culture of Scientific Research through Personal Archives

This project will involve a detailed mapping of the key personal relationships of 20th century British scientists to shed light on the nature, communication and reception of scientific research. It will draw on the Library’s Contemporary Archives and Manuscripts collections, which include personal archives and correspondence from the fields of computer science and programming, cybernetics and artificial intelligence, as well as evolutionary, developmental and molecular biology. As well as being situated within social and cultural history, particularly the history of science and the history of ideas, this cross-disciplinary project is applicable to research in areas such as social anthropology, sociology and social network analysis. It will open up a nuanced understanding of the BL’s collection of the personal archives of twentieth century British scientists. It will enable us to better exploit these valuable collections to research audiences across a number of disciplines.

Hans Sloane’s Books: Evaluating an Enlightenment Library

SloaneEngravedPortraitCroppedThis Digital Humanities projectwill evaluate the library of Hans Sloane (1660-1753): physician, collector and posthumous ‘founding father’ of the British Museum. For over sixty years, Hans Sloane was a dominant figure on London’s intellectual and social landscape. At the heart of his vast collections stood a library of 45,000 books, which – alongside his voluminous correspondence and thousands of prints, drawings, specimens and artefacts – bears witness to his central position in a globalised network of scientific discovery. The CDP project will apply digital techniques to exploit the raw data on over 32,000 items in the Sloane Printed Books Catalogue, and will break new ground by developing digital tools to cross reference, contextualise and analyse the data. This will forge fresh insights into how medical and scientific knowledge was gathered and disseminated in the pre-Linnaean period, with relevance to the history of science, medicine and collecting.

 

Moving beyond our science collections, there is also a third CDP opportunity for a project on ‘Digital Publishing and the Reader’. This will investigate the changing nature of publishing in digital environments to consider how new communication technologies should be recorded or collected as part of a national collection of British written culture.

Applications are invited from academics to develop any of these research themes with a view to co-supervising a PhD project with the British Library from October 2016. Our HEI partners receive and administer the funds for a full PhD studentship from the AHRC and, in collaboration with the Library, oversee the research and training of the student. We provide the student with staff-level access to our collections, expertise and facilities, as well as financial support for research-related costs of up to £1,000 a year.

View further details and application guidelines.

To apply, send the application form to [email protected] by 27 November 2015.

 

04 October 2015

From fiction to fact: the science of Animal Tales

Alice Kirke investigates the facts behind the fiction of the British Library’s Animal Tales exhibition.

The Animal Tales exhibition at the British Library explores what our portrayal of animals within literature tells us about ourselves. The natural environment and its inhabitants have inspired generations of writers, but how do some of our favourite, anthropomorphised fictional creatures compare to their real-life counterparts? I set out to discover what the science says about the creatures lurking among the pages.

Cats: aloof and independent?

Valued for their companionship, skill in hunting vermin, and role in numerous ‘funny cat videos’ on YouTube, the domestic cat was first classified as ‘Felis catus’ by the Swedish botanist and zoologist Carolus Linnaeus in 1758. The exhibition features French philosopher Michel de Montaigne’s Essays,[1] in which he famously asked ‘When I am playing with my cat, how do I know she is not playing with me?’ People have kept cats as pets for thousands of years. Though they are commonly thought to have first been domesticated by the Ancient Egyptians, who considered them to be sacred, there is evidence of earlier domestication dating from around 9,500 years ago.[2] There are many theories and misconceptions about the behaviour of these enigmatic pets. As predators, cats are very focussed on their environment leading to the common misreading of their behaviour as aloof, and although they are seen as ‘independent’ they are in fact social animals. Cat communication includes a variety of vocalizations as well types of cat-specific body language.[3]

 

Snakes: slithering and sinister?

Lamia
A 17th century depiction of Lamia from Edward Topsell's The History of Four-Footed Beasts L.R.301.cc.3.

Snakes have a sinister reputation in literature and culture. In ancient Greek mythology Lamia, the mistress of Zeus was transformed into a terrifying serpentine demon by Zeus’ jealous wife Hera. In Keats’ poem Lamia[4], displayed in the exhibition, the protagonist appears in her beautiful human form before being transformed back into a serpent at her wedding feast. To an extent, this was a comment on science itself; knowledge of the natural world destroyed its beauty.

 

 

 Snakes are perhaps so often portrayed as evil in literature because some species are dangerous to humans, but snakes are diverse creatures- there are over 3,000 species of snake in the world, with at least one type of snake on every continent except Antarctica. There is debate among evolutionary psychologists over whether the fear of snakes is innate. Since those with a phobia of snakes would be more likely to stay away from them and avoid the dangers of being bitten, they had a better chance of surviving and passing on their genes. Recent research suggests that although the fear of snakes is a learned behaviour, people do have a knack for spotting them; when shown images of snakes surrounded by objects of a similar colour babies and young children detected snakes faster than other objects.  

Spiders: creepy crawlies?

Frequent scare stories in the UK press about invasions of deadly spiders prey on a common fear of arachnids. There are over 40,000 different species worldwide, and although the vast majority are venomous most are not dangerous to humans. Arachnologists, experts who study spiders emphasise their diversity in terms of their appearance, habitats and behaviour.

Due to their wide range of behaviours, they have become symbolic of various attributes, including patience, cruelty and creativity in art and mythology.  The character of Anansi, a spider who often acts and appears as a man in West African and Caribbean folklore, has taken on a variety of different traits over time. Anansi Company,[5] featured in the exhibition, is a modern version of tales about Anansi and his friends which are central to Caribbean culture.

Crow: cruel or cunning?

Crow
The Crow and the Pitcher, illustrated by Milo Winter in 1919

In common English, corvids including crows, ravens, rooks, jackdaws, jays and magpies, are all known as ‘the crow family’.  Ted Hughes’ Crow draws on mythology surrounding the much maligned creature, which is often connected with death.[6] In Irish mythology, crows are associated with Morrigan, the goddess of war and death, and the collective name for a group of crows is a ‘murder’. However, they have also been linked with prophesy, cunning and intelligence. In one of Aesop’s fables, a thirsty crow spied a pitcher containing a small amount of water, which was out of reach of its bill. The crow began dropping pebbles into the pitcher one by one, thereby raising the level of water and enabling it to drink. A 2009 study published in Current Biology which replicated Aesop's fable, found that four captive rooks used stones to raise the level of water in a container, allowing a floating worm to move into reach, showing that the goal-directed behaviour of Aseop’s crow is reflected in actual corvid behaviour. European magpies have demonstrated self-awareness in mirror tests, and crows and rooks have been shown to have the ability to make and use tools, previously regarded as a skill specific to humans and a few other higher mammals. This scientific research suggests that crows are one of the most intelligent animals in the world.

Animal Tales showcases many more familiar yet enigmatic creatures. The wealth of material in the Library collections can be used to trace animals in literature as well as the latest scientific research about their characteristics- come and see the exhibition and follow up with some research into your favourite fictional beasts!



[1] Michel de Montaigne, Les Essais de Michel Seigneur de Montaigne. (Paris, 1602) C.28.g.7

[2] Vigne JD, Guilaine J, Debue K, Haye L, Gérard P (April 2004). "Early taming of the cat in Cyprus". Science 304 (5668): 259

[3] Dennis C. Turner, and Patrick Bateson, The domestic cat: the biology of its behaviour. (Cambridge : Cambridge University Press, 2000) m00/46105

[4] John Keats, Lamia, Isabella, the Eve of St. Agnes & other poems. (Waltham St. Lawrence, 1928) C.98.gg.16

[5] Ronald King & Roy Fisher, Anansi Company. (London, 1992) C.193.c.8

[6] Ted Hughes & Leonard Baskin, Crow: from the life and songs of the Crow (London, 1973)

30 September 2015

Overpowered! The Science and Showbiz of Hypnosis

Performer and entertainer Christopher Green's new book "The Science & Showbiz of Hypnosis" is published by British Library Publications on 16th October 2015. In this blog post Christopher explores the intriguing history of hypnosis and investigates some of the science behind this curious practice. Hear more from Christopher at the launch event at the British Library on 13th October. Tickets are available here.

OverpoweredWhat we call hypnosis now has been going on in our brains since we were first human, and it will carry on until there are no more humans.  At this stage of our cultural development we happen to call it hypnosis.  It also happens to be regarded by the vast majority of human beings as something of a joke, by many others as irrelevant and, even those of us who are fascinated tend to focus more on the big moustaches and kitchsy, campy, quirky notions of the big-mouthed practitioners of the subject.  But it belongs to all of us.  It’s a human process.  What exactly is going on chemically, biochemically and bioelectrically isn’t known, but we are fools if we think it’s just the preserve of fellas in spandex shirts.  It’s the people in the white coats that we should be interested in.  Especially in our age of increasing mental dis-ease.  These days, it’s much more acceptable to alter your brain chemistry using powerful drugs in the hope that a tiny percentage of it’s efficacy will help with lifting your mood.  And yet, harnessing what is after all a perfect natural human process – one person simply helping another to experience something – is thought of as a bit sinister and weird.  So I salute the neuro-hypnotism research.  I suspect in a few hundred years when some irreverent and light-hearted comedian writes a round up of their thinking of hypnosis using books from our time, that they look at this and say “Christopher was over-focused on type-face, bill matter and moustaches, but he was right about the neuro-science.  It was, after all, what they called hypnosis back then, that proved the turning point in helping human beings fight back from the damaging mental ill-health caused by fighting the squishing effects of capitalism on a daily basis”.  I can dream, can’t I?

Karlyn
Christopher's second favourite old-time hypnotist 'Karlyn'

This stuff might only be taken seriously once we move on from the word ‘hypnosis’.  It needs serious rebranding.  I think that’s a shame, because as you see from this book, I celebrate all the bright shouts and all the dark shameful whispers in the history of the hypnosis, but to the average person it’s too bleedin’ confusing.  Could it be time to change the name?  A modern day hypnotic hero is Dr Amir Raz.  He started off as a magician while studying to be a doctor.   He says “Magic taught me a lot about psychology in terms of attention, directing attention and how the mind works. At one point I started reading about hypnosis and decided to marry the two."  But he acknowledges the need for the rebrand and I like his solution, although it’s a bit worthy and not spunky enough. 

"Hypnosis is tricky because it has such a checkered history. Many people feel uncomfortable with it, even within the scientific community, because they think it's not something that a serious scientist should get involved in. Part of the reason it has this bad reputation is because of things like stage hypnosis, where you see a bunch of people clucking like chickens."  Dr Raz suggests ditching "hypnosis" in favour of "focused attention" or "susceptibility to suggestion”.

This is not a million miles away from the term coined by James Coates in 1905 “suggestive therapeutics” though as I’ve pointed out in my book, this is likely to get people in cahoots with pimps rather than psychiatrists.  But though his new names don’t zing, Dr Raz makes a rallying cry for the future of the subject.  "I don't consider myself a hypnosis researcher. If anything, I'm more of a neuroscientist with an interest in attention. I see hypnosis as an interesting tool for illuminating interesting scientific questions about consciousness, volitional control and authorship”

Of course, I want to challenge myself and think of a new term for hypnosis that takes all of the history and all the modern neuroscience into account.  I want to be a 21st Century rebranding Braid.  But then he cocked up with the name Hypnosis, introducing all sorts of notions of sleep etc that have misled people ever since.  I’m sure I’ll do the same.  But I’ll have a go.  Please contact me with your own suggestions and let’s solve this one, fam.

Suggestnosis

Relaxed wakefulness

Suggest-Ability

Attention Therapy

…. or following in the footsteps of the arch egotist hypnotist Walford Bodie who coined the term Bodic Force, I suggest calling it after myself - Green Power.

Oh dear!  Your turn!

Christopher Green

24 September 2015

A novel use of PhD data: Investigating the state of the Dementia Workforce

Katie Howe explains how data from the British Library’s electronic thesis service EThOS has been used in a report into the state of dementia research in the UK.

EThOS is the British Library’s electronic theses service. By working with universities across the UK EThOS is able to provide records for over 400,000 UK PhD theses going back as far as the 19th century. For 165,000 of these PhD theses it is also possible to access a full text version of the document. A key feature of EThOS is that you don’t have to come to the BL to use it - in fact it is accessible from anywhere in the world.

In previous blog posts we have described how EThOS could be a valuable resource for scientific researchers (see here and here). However, as an extensive source of information on PhDs undertaken in the UK, EThOS data can also be used to look at trends in PhD research over time. A recent report by the Alzheimer’s Society illustrates this approach. Graph

The Alzheimer’s Society appointed RAND Europe to produce a report on the state of dementia research in the UK. RAND wished to investigate the dementia workforce pipeline - how many researchers are working on dementia and how this is changing over time. As EThOS contains records for a high (and growing proportion) of recent PhD theses, RAND contacted the EThOS team to ask for their help with this investigation. EThOS Metadata Manager Heather Rosie and her colleagues undertook bespoke analysis for RAND and produced a list of theses awarded from 1970 onwards. The graph above shows the results. Dementia-related PhD research has been steadily increasing over the last 30 years. However, cancer-related PhDs have skyrocketed over the same time frame. Now five times more PhD researchers chose to work on cancer than dementia.

InfographicRAND were also interested in what proportion of PhD students studying dementia stay in the field. To investigate this they traced about 1500 dementia PhD researchers to find out about their career since finishing their PhD. The results show that of those who do complete a PhD in dementia, retention in the field is poor with 70% leaving the field within four years. Only 21% are still researching dementia. (The results are summarised on the infographic opposite. A full version of which can be seen here)

The researchers gave a number of reasons for leaving the field of dementia but amongst the most common was a concern over the increasing competition for senior faculty positions. This is not a problem unique to dementia research but spans all of academia. This is a familiar issue for us in team ScienceBL and a previous series of blog posts outlines some alternative career options for those undertaking biomedical PhDs (here and here).

As well as being a great source of detailed information for scientific researchers, PhD theses accessed through EThOS can be used to find out about individual researchers or to help students structure their own PhD thesis. This report shows another novel use of PhD data enabled by the size and national scope of the EThOS resource. The full report can be seen here.

Katie Howe

25 August 2015

Seals, Science and Nations

In this blog post Helen Cowie, Eccles Centre for American Studies Visiting Fellow, writes about her research on the sealskin industry in late-nineteenth century Alaska. Helen will discuss her research as part of the Eccles Centre Summer Scholars Seminar Series

On 17 January 1891, the satirical magazine Punch published a cartoon showing a seal emerging from a hole in the ice. The cartoon depicts the animal propped up on its flippers and looking sagely at two squabbling men. The man on the left, in stripy trousers and cravat, represents the USA, embodied in the familiar character of Brother Jonathan. The rotund man on the right, with bulging stomach and a broad-brimmed souwester, is John Bull, a caricature of Great Britain. The seal addresses them both with soulful gaze, imploring them to ‘avast quarrelling! Give me a “close time” and leave the “sea” an open question’.[1]

YPP_15062015123210_001 - Copy - CopyPunch’s pithy cartoon was a humorous take on a serious international dispute over the future of the fur-seal fisheries of Alaska. Since the early nineteenth century, the fur seal had been hunted extensively in the Bering Sea for its valuable coat, which was used to manufacture ladies’ cloaks and jackets. By the 1890s, however, seal numbers were fast decreasing, triggering mutual recriminations between the USA and Canada. According to naturalist Henry Elliott, who visited the fur-seal islands of St Paul and St George in the summer of 1890, there were only 959,000 seals present during the breeding season; just a third of the number he had seen two decades earlier in 1874.[2]

 The fur-seal controversy centred on the different methods of hunting the animal. The USA hunted the seals on land on the Pribilof Islands, driving young male animals to a designated killing grounds and there bludgeoning them to death. The Canadians hunted the seals at sea, shooting them and spearing them with harpoons in the water. Pelagic sealing (hunting at sea) was regarded as more wasteful, since it killed females, pups and unborn young indiscriminately and mortally wounded many seals whose skins were not subsequently collected. One critic, D.O. Mills, estimated that ‘every skin placed upon the market by [pelagic sealers] represents the destruction of six or eight seals – an utterly unjustifiable inroad into the vitality of the herds’.[3]

YPP_12062015125231_001 - Copy - Copy
‘Killing a “drive” of fur-seals on St Paul’, The Illustrated London News, 24 June 1893

 Keen to protect the seals from destruction, the USA limited the number that could be killed on the Islands and began deploying naval vessels in the Bering Sea to seize ships engaged in pelagic sealing. The Canadians, however, disputed the US’s rights to board their ships in what they considered to be international waters and appealed to Britain to defend the rights of their sealers. By 1891, when Punch published its cartoon, the two nations were teetering on the brink of war.

DSC02425
‘Seals at Home’, The Animal World, 1 September 1882

 The fur-seal crisis offers an interesting early example of wildlife conservation and its international dimensions. Because the seal was a migratory animal, cross-border cooperation was essential to ensure its survival. The USA could introduce a complete moratorium on the killing of seals on land – as indeed it did in 1911 – but if the Canadians continued to slaughter the animals at sea, their efforts would be futile. Measures taken to protect the fur-seal set a precedent for similar transnational agreements concerning the protection of migratory birds and the preservation of game in colonial Africa.

 Another key aspect of the fur-seal debate was the important role played by scientists in the framing of conservation policy. To understand how best to preserve the species, the US Government commissioned several scientific surveys of Pribilof Islands, all staffed by zoological experts. These individuals conducted careful fieldwork on the islands and offered a detailed understanding of seal behaviour and ecology. They used the latest technology to support their studies, backing up their findings with carefully documented evidence. To show that large numbers of seals wounded by pelagic sealers were not subsequently caught, for example, the 1896 commission cited the case of ‘a wet [i.e. nursing] cow’ found at the bay of Polovina on 23 July ‘with bloody shot holes in her shoulder’.[4] To prove that pups required milk until they left the breeding grounds in November, the scientists killed a selection of the animals and examined the contents of their stomachs, which were found, in the vast majority of cases to be either empty (in the case of orphans) or ‘full of milk’ well into October.[5]

Furseal_drawing650
‘The Countenance of Callorhinus’, Drawing by Henry W. Elliott, Pribilof Islands, 5 July 1872

Scientists’ observations informed government policies and lent weight to proposed conservation measures, much as they do today. They did not necessarily provide definitive answers, however, for it was often the case that different studies arrived at different conclusions. One US scientist, Henry Elliott, for instance, advocated a moratorium on the land drive, because he believed that repeated driving impaired the fertility of male seals. His compatriot, David Starr Jordan, however, refuted this, arguing that the seal’s reproductive organs were ‘withdrawn into the body cavity when he is in motion, thus being entirely protected from injury’.[6] The Canadian Record of Science, meanwhile, reprinted an article on sealing in the South Pacific in 1893 which appeared to show that the damage there was done on land, and not at sea. We can therefore see science being used to support different national and ideological viewpoints.

YPP_15062015123210_001 - Copy - Copy (2)As for the seals themselves, they were rarely consulted in the debate, but Punch at least gave one of them a voice. Next to the arresting image with which this blog post began, the magazine printed a short poem, supposedly written by the seal, in which the plucky animal begs both sides to stop squabbling and ‘Give me a thought in the matter’. In rousing nautical language, the seal complains of being ‘worried and walloped without intermission / Until even family duties quite fail’ - a reference to Elliott’s claim that the seal drive rendered males infertile. He protests loudly that his ‘poor wife and children have not half a chance’ – an allusion to the damage done by pelagic sealing - and he urges both sides to establish a ‘close time’ in which he and his family can recover. Since this is a British publication, it is no surprise that the seal refutes the US’s claim to sovereignty over the entire Bering Sea – ‘Men can’t thus monopolise oceans’. He does, however, advocate ‘compromise’ and friendship between nations, issuing a plea for international peace before he ‘dives under’ the water and departs the scene.[7] 

 Thankfully the seal’s call was heeded and the USA and Britain reached a compromise agreement in 1893. Seals were granted a closed season from 1 May to 1 October and a sixty-mile closed zone around the Pribilof Islands in which no pelagic sealing was permitted. Eighteen years later, in 1911, a further international agreement banned pelagic sealing completely, triggering the recovery of the fur-seal population. In 1920 conservationist William Hornaday described the preservation of the fur-seal as ‘the most practical and financially responsive wildlife conservation movement thus far consummated in the United States’.[8]

 

Helen Cowie is lecturer in history at the University of York. Her research focuses on the history of animals and the history of natural history. She is author of Conquering Nature in Spain and its Empire, 1750-1850 (Manchester University Press, 2011) and Exhibiting Animals in Nineteenth-Century Britain: Empathy, Education, Entertainment (Palgrave Macmillan, 2014).



[1] ‘Arbitration’, Punch, 17 January 1891.

[2] Henry W. Elliott, Report on the Condition of the Fur-Seal Fisheries of the Pribylov Islands in 1890 (Paris:Chamerat et Renouard, 1893), p.91.

[3] D.O. Mills, ‘Our Fur-Seal Fisheries’, The North American Review 151 (September 1890), p.303.

[4] David Starr Jordan, Observations on the Fur Seals of the Pribilof Islands, Preliminary Report (Washington: Government Printing Office, 1896), p.44.

[5] Ibid., p.33.

[6] Ibid., p.38.

[7] ‘Arbitration’, Punch, 17 January 1891.

[8] The Times, 31 August 1920.

05 August 2015

Policy into practice

Applications are now open for RCUK Policy Internships at the British Library at 2016. We are offering up to three NERC/MRC funded PhD students the chance to join us in team ScienceBL and help deliver a TalkScience event. In this blog post former intern Stuart Smith reflects on his Policy Internship placement at the British Library.

P3072475
Stuart (red hat and trousers) in the Falkland islands (Photo: Marju Karlsson)

After finishing my BBSRC policy placement at the British Library in July 2013 and wrapping up my PhD thesis, I went in search of a job. Wishing to find a job that balanced both ecological research and public engagement, I was finally offered a 2-year position leading a Darwin Initiative funded project that aims to build capacity to enhance habitat restoration in the Falklands Islands. Despite only being a small island in sub-Antarctica, with a total population of around 3,000 people, there has consistently been a need to communicate scientific and environmental issues effectively. Working for Falklands Conservation, I have established an island-wide re-vegetation trial using native seeds and I regularly talk about my work to people with a range of backgrounds: farmers, landowners, policymakers, researchers, members of the public and military personnel. And while I might not have the opportunity to get a BBC presenter to pop down to lead a panel debate, like I did my when organising a TalkScience event at the British Library, I find myself involved in outreach activity on a weekly basis, whether writing an article for the Penguin News, the local newspaper, or giving a lesson on seeds or habitat restoration in a school. 

 

Bill.Turnbull.panel.TS21.compressed
Bill Turnbull chairing the TalkScience that Stuart developed and delivered as part of his Policy Internship at the British Library

Following on from work on the Falkland Islands, I am about to start a post-doctoral position at the Norwegian University of Science and Technology (NTNU) in Trondheim, Norway as part of AfricanBioServices, an EU funded project, and will be working in the Serengeti-Mara ecosystem in Tanzania/Kenya. My involvement in the project is to investigate the effect of different land-uses (both wild grazing versus domestic pastoral grazing) on grassland productivity and ecosystem functioning. Again, this role is likely to require excellent communication skills to a wide range of audiences from scientists involved in the international consortium to farmers and landowners on the ground. Even though I am still actively involved in ecological research, the essential skills of effective science communication and outreach are highly valued. The British Library has an incredibly supportive and friendly team and were happy to take on an ecologist, who particularly struggled to wear a tie. I would recommend that every postgraduate should take the opportunity to learn an increasingly important set of skills involved in outreach and public engagement and apply for a science policy placement.

Stuart Smith, BBSRC Science Policy Intern 2013

27 July 2015

King John’s teeth

Julian Walker examines an unusual item included in the British Library's current Magna Carta exhibition and discusses what it might tell us about the infamous King John.

One of the last items to be put into the Magna Carta exhibition was the X-ray of King John’s teeth. Easy to miss, and perhaps something of an oddity, this item could also be read as a key item in the lead up to the agreement at Runnymede on 15th June 1215.

People-king-john
Portrait of King John hunting. The British Library

The story of how the X-ray and the teeth come to be in the exhibition – and the first time I can think of that a body part of a British monarch has been part of a British Library exhibition – goes back to the opening of King John’s tomb in Worcester Cathedral in 1797. The tomb was opened on the request of Valentine Green, an antiquarian and engraver, who had come to doubt that King John’s body was in fact laid within his tomb. The news of the opening attracted large numbers of sightseers, Green’s account reporting that thousands had come to watch; among these was a stationer’s apprentice, William Wood, who is credited with having taken two of the four remaining teeth from King John’s jawbone. The teeth were passed on to Worcester City Museum about 100 years later, where they have remained.

Green’s account of the teeth states that they were ‘quite perfect’, but perhaps we should think of this as a comparative assessment. By the end of the eighteenth century many people’s teeth were affected by decay, the massive increase in the importation and use of sugar during the century not being matched by increasing oral hygiene. This was the period when fashionable people wore ‘plumpers’, pads of cork or cloth in their cheeks to build up the contours of a face following tooth loss. In the thirteenth century there would have been little opportunity for John to get access to cane-sourced sugar, which only very gradually became available across Europe during the period of the crusades. Honey, the only other sweetener available at that time, though it contains fructose and glucose, also carries antibacterial agents which may act to counter some of the effects of the sugars; but honey may also cause caries[i]. Caries was certainly there during the thirteenth century, but perhaps less than might be expected given the lack of dental care[ii].

King John teeth 1216
X-ray of King John's teeth

In 1998 I was engaged on a fine art project at Worcester Museum and Art Gallery, looking at the nature of touch, and persuaded the curator to let me get King John’s teeth X-rayed at a local dental practice.  I later took the X-ray to my own dentist with some questions – one of the teeth was flattened and I wanted to know how this could have happened. If it was caused by grinding did this show evidence of John having to eat gritty bread? Were his teeth ‘quite perfect’? What my dentist pointed out was that dietary effects would be shown on all the teeth; the fact that only one was flattened could only happen as a result of tooth-grinding, whose various forms are known as bruxism. Bruxism is very widespread, seldom severe enough to cause damage to the teeth, but is often related to anxiety and stress. The attritional bruxism in this tooth might have a number of causes: a particular jaw pattern, with one tooth being ground against its opposite, or the eruption of an individual tooth, or a particular diet (my dentist had seen it in cases where the diet included bones). In this situation, and as shown by the X-ray, the enamel and dentin are worn down, potentially exposing the pulp, which tends to shrink back allowing a thin layer of dentin and enamel to slowly build up; but the tooth would have been permanently hypersensitive, producing toothache, headache, possibly earache, and potentially restriction of the ability to open the mouth.

What we have no evidence for at this stage is when or why John started to grind his teeth; was the grinding the result of emerging wisdom teeth and dental crowding early on, and thus present through his adult life? And did he grind his teeth awake or asleep (there is some evidence for hereditary sleeping bruxism)? What we do have evidence for is a family trait that involved a tendency towards outbursts of violent rage in John’s father, Henry II (not just in the Thomas Becket crisis). Anger was a constant in these two kings; R V Turner proposes that the Pipe Rolls of Henry and John show the near-institutionalisation of anger in which the king ‘remitted his anger and indignation against individuals in return for money’[iii]. Crucially with Henry we see dental activity in the context of anger: he is said to have fallen to the floor in rage and chewed the rushes on hearing the King of Scots praised by one of his own men.

What we also have is evidence for John’s taste for soft foods. Though John, in keeping with the customary behaviour of Angevin kings, was by no means controlled in his sexual activity, he clearly exerted control of the sexual activity of others. The Oblate Roll for Christmas 1204 recorded that Joan ‘the wife of Hugh de Neville gives the Lord King 200 chickens in order that she might lie one night with her lord’. This kind of ‘fine’ or ‘tax’ to allow, defer or avoid something was common at the time, and was much used by John. What is interesting here is that the ‘fine’ or ‘tax’ is paid not in money but in the soft and easily chewed meat of the chicken. There is evidence elsewhere of John’s taste for both chicken and indeed eggs – his Christmas feast at Winchester in 1206 involved 1,500 chickens, 5,000 eggs, 20 oxen, 100 pigs, and 100 sheep. Were eggs special to John because they were soft? If John had a permanently sensitive tooth (at least one), and toothache, certainly towards the end of his life, this would have made him irritable, angry, quick to find solace in easy to eat foods (perhaps even those notorious peaches washed down by cider, which allegedly hastened his end).

As regards treatment for toothache, as well as bloodletting, cupping and herbal poultices, some effective painkillers were available – ice, mandrake, henbane, alcohol, and oil of cloves, though this last was fantastically expensive. Gilbert Anglicus, whose Compendium of Medicine was written about 25 years after the death of John, mentions oil of cloves as a treatment for toothache, but conflict at home and on the continent would have hampered its import and transportation.

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The British Library exhibition "Magna Carta: Law, Liberty, Legacy" is open until 1st September

 

How much importance should we put on John’s tooth? Should we build his physical pain into our view of the circumstances that led to Magna Carta? Historiography of the physiology of movers and shakers has always been suspect. There is a perceived danger of reductivism in including Henry VIII’s leg ulcer in the factors leading to his increasingly autocratic reign, or evaluating among the factors leading to the outcome of the Battle of Waterloo Napoleon’s haemorrhoids, which prevented him from supervising the denouement of the battle on horseback. During schools’ workshops in the Magna Carta exhibition I ask students whether they feel King John’s dental distress should be considered as part of historical research and a factor in the story of the document. Mostly they think yes; teachers are less convinced, perhaps wary of the influence of Horrible Histories. I also ask students for suggestions for an exhibition souvenir for British Library shop; my favourite so far has been an eraser in the shape of one of King John’s teeth.

Julian Walker is an artist and writer; he leads workshops for schools and colleges for the British Library Learning Department. He is the author of How To Cure The Plague And Other Curious Remedies and The Finishing Touch - Cosmetics Through The Ages, both published by the British Library. www.julianwalker.net

References 

[i] Compare

Effects of honey, glucose, and fructose on the enamel demineralization depth, Ahmadi-Motamayel, Fatemeh et al., Journal of Dental Sciences , Volume 8 , Issue 2 , 147 – 150

with

Diet, nutrition and the prevention of dental diseases Paula Moynihan1, and Poul Erik Petersen2 1 WHO Collaborating Centre for Nutrition and Oral Health, School of Dental Sciences, University of Newcastle upon Tyne, Newcastle upon Tyne, UK: 2 WHO Collaborating Centre for Community Oral Health Programmes and Research, University of Copenhagen, Copenhagen, Denmark

[ii] Dental caries, tooth wear and diet in an adult medieval (12th–14th century) population from Mediterranean France, Esclassan, R. et al., Archives of Oral Biology, Volume 54 , Issue 3 , pp287 – 297, indicates a 17.5% incidence of caries.

[iii] Turner, R. V., in Loengard, J. S., Magna Carta and the England of King John, 2010, Woodbridge, p17

 

07 July 2015

Inspiring Careers - Part 1

Katie Howe outlines some of the careers advice given at the 2015 Francis Crick Institute post-docs' retreat. The second blog post in this series covers science policy, editorial and academic careers and will be posted tomorrow.

Last month we hosted the 4th Francis Crick institute post-doctoral researchers' retreat, which this year had the theme of 'Inspiring Careers'. With competition for tenured faculty positions greater than ever, post-docs are considering a wide range of careers inside and outside of academia. Many of the British Library’s science team are former biomedical research scientists who have hung up our lab coats to pursue other opportunities, so this is a theme with which we could strongly identify.

There were 11 speakers on the day, each with a different story to tell about how they got to where they are today. This series of two blog posts outlines some of the careers covered during the retreat and brings together a few of the top tips shared by the speakers.

Pharmaceuticals: Klaus Hirzel (Roche) and Neil Torbett (hVIVO)

Klaus outlined his role at Roche showing how a drug progresses from basic research into the clinic. He noted that in terms of day to day work the tasks he carries out are often quite similar to those that might be experienced in an academic research lab.

Neil Torbett
Neil Torbett (Photo: Riccardo Guidi)

Neil Torbett followed Klaus’ introduction by describing his experience in pharmaceutical start-up companies. Following a PhD and post-doc investigating protein phosphorylation, Neil became involved in Piramed, a research collaboration with Genentech that focussed on the discovery and development of PI3-kinase based inhibitors for cancer. This experience paved the way for a career in various biotech companies involved in molecular diagnostics. These start-ups are great examples of the huge potential of interdisciplinary working. For example the biomarker discovery company Activiomics where Neil served as Chief Operating Officer, brought together academics leading in the fields of mass spectrometry and cell signalling into a spin-out company overseen by QMUL’s technology transfer arm. Neil suggested getting in contact with your university’s technology transfer office if you have a project that could be of commercial interest. They can help by providing professional support and vital funding. Neil also noted that the expertise possessed by academics is very much in demand by start-up companies, so if your own research doesn’t have a commercial angle, your skills could be valuable to an existing start up.

Science communication: Dane Comerford (University of Cambridge)

Dane has had a varied career in academia and engagement as well as a brief sojourn to the civil service working in a team dealing with CRB checks and disclosures. But it was Dane’s passion for the hydrogen bond and desire to share its simple beauty and power more widely that led him to try his hand at public engagement.

Dane Comerford
Dane Comerford (Photo: Riccardo Guidi)

By sharing some examples from his portfolio of public engagement activities, Dane illustrated the wide range of opportunities within science communication - from creating films describing scientific concepts to getting involved in international science festivals. A key message of Dane’s talk was to be brave and don’t be afraid to try new things and to “keep your eyes and ears open” for new opportunities. Dane did recognise that without a supportive supervisor getting involved in public engagement can be a challenge but pointed out that Research Council UK-funded researchers are now required to participate in public engagement activities. Communication of and engagement with research is increasingly recognised as a valuable and necessary part of the research process so hopefully any opposition from supervisors is becoming less common.

There are plenty of opportunities to get involved in public engagement within academia. Dane pointed post-docs to the local university public engagement units. The Crick’s communication and engagement team are developing plans for their own programme of public engagement training and have lots of upcoming volunteering opportunities. Over this summer the Crick is attending several local festivals that require volunteers to help deliver science engagement activities, so please keep an eye on CrickNet or email [email protected] to find out more and how to get involved.

(I also recommend the psci-com mailing list for anyone interested in science communication or engagement with any audience - KH).

Education: Bryn James (Researchers in Schools) and Ed Arthur  (TeachFirst)

Ed first outlined the innovative TeachFirst programme. TeachFirst was set up in 2002 and aims to address educational disadvantage by recruiting high calibre graduates to teach in challenging schools. Participants are given an intensive ‘crash course’ in teaching during a six-week long Summer Institute before entering the classroom in September. Professional development and specialist teacher training then continues throughout the two year programme.

Education
Bryn James and Ed Arthur introducing Researchers in Schools and TeachFirst respectively (Photos: Riccardo Guidi)

Some of the key skills required of TeachFirst teachers are resilience, organisation and empathy. The schools that TeachFirst works with often have high levels of economic deprivation which can present many challenges to new teachers as well as exciting opportunities to make a difference. Ed went on to describe the impact of TeachFirst alumni. A third of those who complete the programme stay in teaching after the two years but many go on to leadership positions in other sectors and 36 social enterprises have been formed by TeachFirst alumni.

Bryn then introduced us to Researchers in Schools - a relatively new programme that specifically recruits people with PhDs into the teaching profession. This teacher training route is highly bespoke and designed to utilise participants’ academic experience. Uniquely, participants are given the chance to take one day out of school per week for their own independent research giving them a chance to keep their foot in the door of the lab. The aim of the scheme is to increase subject expertise within non-selective state schools, particularly in science subjects. Another benefit is that by acting as champions of higher education Researchers in Schools teachers can also promote and widen access to the best universities.

Both Ed and Bryn noted how rewarding teaching is as career with Bryn even sharing some of the very touching messages he had received from students thanking him personally for his help and support.

Tune in tomorrow for the second part of this post - featuring careers in science policy, science publishing and academia.

Katie Howe

12 February 2015

Strange Bedfellows

The Knowledge Quarter, with the British Library as its nucleus, is the name given to a London hotspot of technology, knowledge, art and science organisations and - this should be the exciting bit - of interdisciplinary and interpersonal collaboration, and of pulling together resources in new ways. But when George Osborne launched the Knowledge Quarter in December 2014 he was perhaps running to catch up with what has long been hatching here. Laurence Scales looks at three examples from the last 125 years of scientists in the area crossing boundaries.

Big Data

You may have thought that statisticians never bothered in practice with all that coin tossing. Not true! Karl Pearson (1857-1936) ‘occupied part of the vacation of 1892 with 2400 tosses of ten shillings at a time’.

In the wake of Darwin the mechanism and rules of biological inheritance remained obscure and an effort was launched by the Royal Society to probe the subject by conducting statistical inquiries into the measurable characteristics of plants and animals. To this end Pearson established a biometric laboratory at University College London. Unfortunately, in Pearson’s case the quest for understanding nature also became entwined with his Victorian prejudices and he veered off into eugenics. However, in his statistical work he looked for patterns in raw data, investigated covariance (correlation) and revived interest in Bayes’ rule (trying to work backwards from measured probabilities to select between hypotheses).

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Karl Pearson | Wellcome Images (CC-BY)

Pearson recruited skilled human computers armed with mechanical calculators and, when war broke out in 1914, he was able to redeploy them outside biology, providing the government with graphs concerning shipping and imports on which the war effort depended. His team also took on aeronautical and ballistic calculations. Solving these problems required not just brute force but simplification and efficiency.

Pearson had thus developed some of the basic tools of data mining or ‘big data’ analysis, the projected domain of the Alan Turing Institute which has a place reserved in the Knowledge Quarter. The Francis Crick Institute behind the British Library will, no doubt, be using such algorithms to mine data from medical records.

Knowledge and Collaboration

About a kilometre north west from the British Library is the last home of molecular biologist J. D. Bernal (1901-1971). In 1943 Bernal worked for Combined Operations Headquarters, a collaboration of army, navy and air force then focused on planning the 1944 invasion that liberated Europe. This may just sound like an exercise in military might but preparations also necessitated the use of every possible source of information.

A lesson from that campaign is that collaboration is not always the automatic and harmonious outcome of proximity. Chief of Combined Operations, Lord Louis Mountbatten, knew that he had not only to shake his headquarters service chiefs out of their grooves but also inject new knowledge and imagination to solve military problems. Bernal was one of those he recruited for the purpose. Habitual secrecy also had to go: Bernal could not provide a good answer until he was sure he was being asked the right question.

NormandySupply_edit
Normandy Supply | Wikimedia Commons (Public domain)

Bernal possessed extraordinary knowledge and intellect, not limited to molecular biology. (But he once remarked, when pressed, that he knew nothing at all about the fourth century in Romania.) He set about investigating, without having access to the Normandy beaches, the physics of waves and sand and the shoreline geology of the area. An important source was the British Museum (the British Library’s former home). He began by consulting a pre-war guide book. Eventually, his desk was even strewn with reports in Latin. The Romans used certain areas of Normandy as a source of peat for fuel, and peat meant peat bogs, unsuitable ground for assault vehicles. The invasion plans of 1944 reflected this accordingly and were largely successful – something else you might not have known that the Romans did for us.

Art and Science

In 2013 visitors to the London Canal Museum, a few blocks north east of the British Library, were invited to don a hard hat to descend into the dank Victorian ice wells. For a few weeks the caverns which once stored Norwegian ice to preserve London’s fish and freeze its ice cream were home to Covariance, a sparkling art installation inspired by subterranean particle detectors and sponsored by the Institute of Physics. (Both organisations are near neighbours and now KQ partners).

Img_8735
"Covariance" Tim Lewis | London Canal Museum

Covariance was a way for both parties to engage with new audiences and the museum also used IT to make the artwork accessible for those unable to visit or scale a ladder. We don’t yet know whether any new ways of processing particle data have emerged from looking at the artist Lyndall Phelps’ glistening ‘diamantes’. While the ice wells may well have turned some young minds towards ice cream, it might just also have turned a few in new directions.

Laurence Scales, www.laurenceswalks.co.uk , @LWalksLondon

Laurence leads unique and eclectic London tours focused on the history of discovery, invention and intelligence, most recently one devoted to Geeky Ladies.  He is a graduate in engineering and has worked in various technological industries.

Further reading

J. D. Bernal, The Sage of Science by Andrew Brown, 2005

When Computers Were Human by David Alan Grier,2005

The Theory That Would not Die by Sharon Bertsch McGrayne, 2011

The Watery Maze: The Story of Combined Operations by Bernard Fergusson, 1961

Oxford Dictionary of National Biography, On-Line Edition

06 February 2015

DataCite Case Study: ForestPlots.net at the Unviersity of Leeds

In June last year, we held a DataCite workshop hosted by the University of Glasgow. We've now turned our speaker's use of Digital Object Identifiers (DOIs) for rainforest data into a video and printed case study.

You can still find a short summary of that event here. Our thanks go to Gabriela Lopez-Gonzalez for taking the time to come and film with us.

 

We hope that this case study will help institutions promote the idea of data citation and use of DOIs for data to their researchers, and that this in turn will encourage more submission of data to institutional repositories.

 

A DataCite DOI is not just for data

During January we had also been trying to spread the word that DOIs from DataCite aren't necessarily just for data. We've been working with the British Library's EThOS service to look at how UK institutions might give DOIs to their electronic theses and dissertations.

There was an initial workshop to divine the issues in November 2014, and on 16th January we held a bigger workshop, bringing more institutions together to look at how we might start to establish a common way of identifying e-theses in the UK.

The technical step of assigning a DOI to a thesis is relatively straightforward. Once an institution is working with DataCite (or CrossRef) they can use their established systems to assign a DOI to a thesis. But the policies surrounding the issue and management of this process are more complex. We're hoping that these workshops have helped everyone to pull in the same direction and collaborate on answers to common questions.

This work has given rise to a proposal to look at how to improve the connection between a thesis and the data it is built on. By triggering the consideration of sharing the data supporting a thesis, maybe we can "get 'em young" and introduce good data sharing practice as early in the research career as possible. Connecting the thesis and its data also increases the visibility of both, helping early career researchers to reap the benefits of their hard work sooner.

Watch this space to see what happens next!

 

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