Dame Anne McLaren: a noted career
To celebrate the broadcast of the Sky Arts series, Treasures of the British Library, we are publishing a number of articles in the coming weeks on people whose work features in the six-part programme. We begin today with Dame Anne McLaren whose notebook was one of the items chosen by Professor Lord Robert Winston.
Dame Anne McLaren (1927–2007) was a developmental biologist who pioneered techniques that led to human in vitro fertilisation (IVF).
Emma Wesley, ‘Dame Anne McLaren DBE, FRS, FRCOG’ (2010). Collection of the Royal Society, London. Copyright Emma Wesley
McLaren studied Zoology at Oxford and received a DPhil in 1952. In the same year she moved to UCL and began research with her husband Donald Michie into the skeletal development of mice. In 1955 she and Michie moved to the Royal Veterinary College and it was in 1958, while working with John Biggers, that McLaren produced the first litter of mice grown from embryos that had been developed outside the uterus and then transferred to a surrogate mother. This work paved the way for the development of IVF technologies and the birth of the first IVF baby Louise Brown some 20 years later.
Detail from McLaren’s laboratory notebook dated 1955-1959 recording her experiments concerning embryo transplants in mice. (Add MS 83844). Copyright the estate of Anne McLaren.
Detail from Mclaren’s laboratory notebook dated 1968-1976. (Add MS 83854). Copyright the estate of Anne McLaren.
In later years Anne’s career took her from Edinburgh to Cambridge via UCL where she continued her work into fertility and reproduction. As well as undertaking research she was a keen advocate of scientists explaining their work to the population at large and being involved in the formation of public policy. McLaren was a member of the Warnock committee whose advice led to the Human Fertilisation and Embryology Act of 1990 as well as the establishment of the Human Fertilisation and Embryology Authority, which regulated in vitro fertilization and the use of human embryos, on which she served for over 10 years.
Selection of lectures dating from 1977-78 including a ‘Lecture to girl’s school near York’ (Add MS 83835). Copyright the estate of Anne McLaren.
The Anne McLaren papers at the British Library consist of letters, notes, notebooks and offprints. These are currently available to readers through the British Library Explore Archives and Manuscripts catalogue at Add MS 83830-83981.
Additionally one of Anne McLaren’s notebooks containing material from 1953 to 1956 (Add MS 83843) is on long-term display in the British Library’s Treasures Gallery.
Anne McLaren’s scientific publications and books are available to readers via the British Library Explore catalogue.
Jonathan Pledge
Curator, Contemporary Archives and Manuscripts